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ea0035p1060 | Thyroid (non-cancer) | ECE2014

THRB expression is affected by miR-26a and miR-496, but age-associated decrease of the expression of this gene in human peripheral blood mononuclear cells is not dependent on these miRNAs

Pawlik-Pachucka Eliza , Budzinska Monika , Domaszewska-Szostek Anna , Owczarz Magdalena , Gewartowska Magdalena , Kurylowicz Alina , Puzianowska-Kuznicka Monika

Introduction: Decreased function of the thyroid axis during aging is associated with a better functional performance and longer survival. This phenomenon can be a result not only of a lower production of thyroid hormones including bioavailable triiodothyronine, but also of age-associated alterations regarding triiodothyronine receptors.Methods: Functional studies regarding interaction between the 3′UTR of TRβ1 mRNA and in silico-ident...

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Endocrine Abstracts

THRB expression is affected by miR-26a and miR-496, but age-associated decrease of the expression of this gene in human peripheral blood mononuclear cells is not dependent on these miRNAs

BiosciAbstracts